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肖玉秀

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姓名:肖玉秀                       

性别:

职务、职称:博士,教授,博士生导师

通讯地址:湖北省武汉市武昌区东湖路 185, 430071

办公地点:武汉大学医学部5号楼904

电话: 027-68759892

传真: 027-68759850

E-mail: yuxiuxiao2011@whu.edu.cn

 

学习简历:

2003 武汉大学化学与分子科学学院分析化学专业,理学博士。

1994 中国药科大学药学院药物分析专业,理学硕士。

1991 武汉大学化学系,理学学士。

 

工作简历:

2007-现在  武汉大学药学院,教授/博士生导师

2005-2010  武汉大学药学院,教授/博士生导师,副院长

2002-2007  武汉大学药学院 副教授

2001-2002  美国Iowa State University,访问学者

1994-2001  武汉大学生命科学学院,讲师

 

社会兼职:

中国医药生物技术协会药物分析技术分会常务委员

中国药理学会分析药理学专业委员会委员

国家继续医学教育学科专家组成员

国家留学基金委评审专家

国家科学技术奖评审专家

国家双语教学示范课程建设项目通讯评审专家

国家自然科学基金项目通讯评审专家

全国优秀博士学位论文通讯评审专家

 

研究领域:药物分析学

 

研究兴趣与方向:

样品预处理;生物医药分析新方法;药物筛选;药物质量控制。

 

主持学术研究课题:

国家自然科学基金面上项目(81673394

国家自然科学基金面上项目 (81373045

国家自然科学基金面上项目(20575050

湖北省自然科学基金重点项目(2015CFA139

湖北省自然科学基金面上项目 (131137)

湖北省自然科学基金面上项目 (131763)

湖北省自然科学基金面上项目(130423

中央高校基本科研业务费专项资金项目(2081006

中药质量标准研究校企合作项目

 

教学及教学研究课题:

1. 主讲本科生课程《药物分析学》、研究生课程《药物代谢与体内药物分析》

2. 主持教学研究课题:

湖北省精品课程《药物分析》建设项目;

武汉大学研究生精品课程建设项目《药物代谢与体内药物分析》;

武汉大学教学改革建设项目药物分析学理论与实验教学的改革研究JG201469;

武汉大学教学研究重点项目《药物分析学》大类平台课程建设与质量提升研究” (413200018)

 

近年发表的代表性论文:

1.   Long Yu#, Qutong Zheng#, Di Wu, Yuxiu Xiao*. Bimetal-organic framework nanocomposite based point-of-care visual ratiometric fluorescence pH microsensor for strong acidity. Sensors & Actuators: B. Chemical, 294 (2019) 199–205.

2.   Anqi Huang#, Wenwen Deng#, Dandan Wu, Shuwen Wu, Yuxiu Xiao*. Hexafluoroisopropanol-salt aqueous two-phase system for extraction and purification of chlorogenic acid from ramie leaves. Journal of Chromatography A, 1597 (2019) 196–201.

3.   Jia Chen, Wenwen Deng, Xiao Li, Xuanxuan Wang, Yuxiu Xiao*. Hexafluoroisopropanol/Brij-35 based supramolecular solvent for liquid-phase microextraction of parabens in different matrix samples. Journal of Chromatography A, 1591 (2019) 33–43.

4.   Wenwen Deng#, Long Yu#, Xiao Li, Jia Chen, Xuanxuan Wang, Zixin Deng, Yuxiu Xiao. Hexafluoroisopropanol-based hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of pyrethroids in tea beverages and fruit juices. Food Chemistry, 274 (2019) 891–899.

5.   Yu Zong#, Jia Chen#, Jinxuan Hou, Wenwen Deng, Xiaoyan Liao, Yuxiu Xiao*. Hexafluoroisopropanol-alkyl carboxylic acid high-density supramolecular solvent based dispersive liquid-liquid microextraction of steroid sex hormones in human urine. Journal of Chromatography A, 1580 (2018) 12–21.

6.   Jia Xu#, Xiao Li#, Cao Li, Jia Chen, Yuxiu Xiao*. Hexafluoroisopropanol-induced salt-free catanionic surfactant coacervate extraction method for determination of fluoroquinolones in milk samples. Food Chemistry, 242 (2018) 122–130.

7.   Yunfang Li#, Ping Zhao#, Yu Chen, Yanze Fu, Kuan Shi, Liu Liu, Hui Liu, Mingrui Xiong, Qing-Hua Liu, Guangzhong Yang*, Yuxiu Xiao*. Depsidone and xanthones from Garcinia xanthochymus with hypoglycemic activity and the mechanism of promoting glucose uptake in L6 myotubes. Bioorganic & Medicinal Chemistry, 25 (2017) 6605–6613.

8.       Jia Xu,Yunfang Li,Cao Li,Rui Zhang,Yuxiu Xiao*. Hexafluoroisopropanol-mediated cloud point extraction of organic pollutants in water with analysis by high-performance liquid chromatography. Anal Bioanal Chem, 2017, 409:4559–4569.

9.       Wen-Wen Deng, Yu Zong, and Yu-Xiu Xiao*. Hexafluoroisopropanol-Based Deep Eutectic Solvent/Salt Aqueous Two-Phase Systems for Extraction of Anthraquinones from Rhei Radix et Rhizoma Samples. ACS Sustainable Chem. Eng., 2017, 5, 4267-4275.

10.   Jia Xu, Manli Niu, Yuxiu Xiao*. Hexafluoroisopropanol-induced catanionic surfactants based coacervate extraction for analysis of lysozyme. Anal Bioanal Chem, 2017, 409:1281–1289

11.   Yu Tian#, Ran Wei#, Bo Cai, Jinfeng Dong, Bin Deng, Yuxiu Xiao*. Cationic gemini pyrrolidinium surfactants based sweeping-micellar electrokinetic chromatography for simultaneous detection of nine organic pollutants in environmental water. Journal of Chromatography A, 1475 (2016) 95–101.

12.   Cao Li#Jia Xu#Dan ChenYuxiu Xiao*. Detection of phthalates migration from disposable tablewares to drinking water using hexafluoroisopropanol-induced catanionic surfactant coacervate extraction. Journal of Pharmaceutical Analysis, 6 (2016): 292-299.

13.   Yunfang Li, Jia Xu, Yu Chen, Zhinan Mei, Yuxiu Xiao*. Screening of inhibitors of glycogen synthase kinase-3β from traditional Chinese medicines using enzyme-immobilized magneticbeads combined with high-performance liquid chromatography. Journal of Chromatography A, 1425 (2015) 8–16.

14.   Yu Tian, Yunfang Li, Jie Mei, Bo Cai, Jinfeng Dong, Zhiguo Shi, Yuxiu Xiao*. Simultaneous separation of acidic and basic proteins using geminipyrrolidinium surfactants and hexafluoroisopropanol as dynamic coating additives in capillary electrophoresis. Journal of Chromatography A, 1412 (2015) 151–158.

15.   Yu Tian, Yunfang Li, Jie Mei, Bin Deng, Yuxiu Xiao*. Hexafluoroisopropanol-modified cetyltrimethylammoniumbromide/sodium dodecyl sulfate vesicles as a pseudostationary phase in electrokinetic chromatography. Journal of Chromatography A, 1404 (2015) 131–140.

16.   Yao Xiao, Yunfang Li, Jinjin Ying, Yu Tian, Yuxiu Xiao*, Zhinan Mei**. Determination of alditols by capillary electrophoresis with indirect laser-induced fluorescence detection. Food Chemistry, 2015, 174: 233–239.

17.   Bin Deng, Yu Tian, Xu Yu, Jian Song, Feng Guo, Yuxiu Xiao*, Zhiling Zhang**. Laminar flow mediated continuous single-cell analysis on a novel poly(dimethylsiloxane) microfluidic chip. Analytica Chimica Acta, 2014, 820: 104-111.

18.   Yunfang Li, Yu Chen, Chuying Xiao, Dan Chen, Yuxiu Xiao*, Zhinan Mei**. Rapid screening and identification of alpha-amylase inhibitors fromGarcinia xanthochymus using enzyme-immobilized magneticnanoparticles coupled with HPLC and MS. Journal of Chromatography B, 2014, 960: 166–173.

19.   Bin Deng, Zhi-Ming Wang, Zi-Hao Zhou, Yi-Meng Liu, Jian Song, Yu-Xiu Xiao*. Quantitative study of cellular heterogeneity in doxorubicin uptake and its pharmacological effect on cancer cells. Biomedical Chemistry 2014, 2014, 28: 1393–1401.

20.   Dan Chen, Pei Zhang, Yunfang Li, Zhinan Mei, Yuxiu Xiao*. Hexafluoroisopropanol-induced coacervation in aqueous mixed systems of cationic and anionic surfactants for the extraction of sulfonamides in water samples. Anal Bioanal Chem 2014, 406(24) : 6051-6060.

 

利:

1. 肖玉秀,邓彬. 一种两用激光诱导荧光检测系统. 专利号:ZL 201310012461.6, 证书号:第1650205号,授权公告日:2015429

2. 肖玉秀,吴喆,梅洁. 一种混合表面活性剂双水相萃取体系. 专利号 201110287840.7,授权公告日:2014415

3. 肖玉秀, 徐见容. 一种用于正交式激光诱导荧光检测器的四维可调毛细管夹持器. 专利号 ZL 200820230546.6, 授权公告日2009109

4. 肖玉秀,徐见容,倪峙旭. 一种毛细管窗口制作器. 专利号 ZL 200920084847.7,授权公告日2010512

5. 肖玉秀,汪志明,徐见容,倪峙旭. 一种毛细管冲洗及进样两用器. 专利号 ZL 200920228727.X,授权公告日201069

 

招聘信息:诚邀博士后加盟本课题组。欢迎校内外优秀学生报考本课题组博士生、硕士生。


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