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Professor

Position: Professor

School/Academic Group: School of Pharmaceutical Sciences

Email: yuxiuxiao2011@whu.edu.cn

Education

1991 Wuhan University, bachelor

1994 China Pharmaceutical University of Science in Pharmaceutical Analysis, master

2003 Wuhan University, Ph.D.

Professional Memberships and/or Notable Appointments:

Drug Analysis Technology Branch, China Medicinal Biotech Association, Standing Committee Member

Analytical Pharmacology Specialty Committee, Chinese Pharmacological Society Committee Member

Working Experience

1994 - 2001 Wuhan University of Life Sciences, teaching assistant, lecturer

2001 - 2002 Iowa State University, Visiting Scholar

2002 - 2007 Wuhan University of Pharmacy, Associate Professor  

2005 - 2010 Wuhan University of Pharmacy, Professor

2007 - now Wuhan University of Pharmacy, Professor


Current Teaching Interests/Responsibilities:

Pharmaceutical Analysis

Research Interests:

Design, Synthesis, and Pharmaceutical Analysis Applications of Novel Nanomaterials and Green Solvents; Drug Screening

Publications

1. Qi Xu#, Shuo Wang#, Zhiwen Gan, Yongzhen Liu, Long Yu*, Hong Cheng*, and Yuxiu Xiao*. Time-Resolved Levodopa Cascade Polymerization Tuned by Bimetallic MOF Fluorescent Nanozyme and Boric Acid for Butyrylcholinesterase Activity Dual-Mode Assay. Analytical Chemistry, 2024, 96: 20635–20644.

2. Yumin Feng#, Long Yu#, Qi Xu; Zhongyu Wei, Zhiwen Gan, Xilin Nie*, Yuxiu Xiao*. Bioreaction-Compatible Bivariate Lanthanide MOF Sensor Enables Stimulus-Multiresponsive Platform for ctDNA On-Site Detection, Analytical Chemistry, 2024, 96: 10953–10961.

3. Long Yu#*, Yongjin Shen#, Qi Xu; Zhiwen Gan, Yumin Feng, Chunxu Yang*, Yuxiu Xiao*. Enhancing Kinase Activity Detection with a Programmable Lanthanide Metal–Organic Framework via ATP-to-ADP Conversion. Analytical Chemistry, 2024, 96: 12139–12146.

4. Long Yu, Qi Xu, Yuqing Sun, Yuhao Wang, Yongling Tang, Qianqian Yuan, Shuang Peng*, Gaosong Wu*, Yuxiu Xiao*, Xiang Zhou. Programmable Lanthanide Metal–Organic Framework for Ultra-Efficient Nucleic Acids Extraction and Interaction Analysis. Analytical Chemistry, 2024, 96: 11455–11462.

5. Peng*, Yuxiu Xiao*. Bioinspired Heterocoordination in Adaptable Cobalt Metal–Organic Framework for DNA Epigenetic Modification Detection. Analytical Chemistry, 2024, 96: 9984–9993.  

6. Shuo Li#, Qingrong Chen#, Qi Xu#, Zhongyu Wei#, Yongjin Shen, Hua Wang, Hongbing Cai*, Meijia Gu*, Yuxiu Xiao*. Hierarchical Self‐Assembly Molecular Building Blocks as Intelligent Nanoplatforms for Ovarian Cancer Theranostics. Advanced Science, 2024, 11: 2309547.  

7. Shuo Wang, Zhongyu Wei, Qi Xu, Long Yu*, Yuxiu Xiao*. Trinity strategy: enabling perovskite as hydrophilic and efficient fluorescent nanozyme for constructing biomarker reporting platform. ACS Nano, 2024, 18: 1084–1097.  

(8) Zhongyu Wei#, Shuo Wang#, Qi Xu, Shuo Li, Long Yu* and Yuxiu Xiao*. Macrophage-Inspired Degradation-Activation System Enables Ultrasensitive Multicolor Detection of Haloacetic Acids via Janus Perovskite Halide Exchange. Analytical Chemistry, 2023, 95: 11695–11705.

9. Long Yu#, Lixiang Feng#, Zhongyu Wei, Shuo Wang, Yumin Feng, Yongjin Shen, Junlong Cai, Jianyuan Wu* and Yuxiu Xiao*. Tunable Fluorescent Artificial Receptor Biosensor Based on Programmable Lanthanide Metal-Organic Framework for Highly Selective Neurotransmitter Detection. Advanced Functional Materials, 2023, 33: 2300309.

10. Shuo Wang, Zhongyu Wei, Long Yu, Jinxuan Hou*, Gaosong Wu*, Yuxiu Xiao*. Halide salt-tuning at interface: Highly Water-stable and Anion-exchange-active CsPbX3@SiO2 Trimurti Nanoparticles for Multicolor Metabolite Assay. Chemical Engineering Journal, 2023, 468: 143503.

11. Shuo Li#, Zhongyu Wei#, Li Xiong, Qi Xu, Long Yu* and Yuxiu Xiao*. In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal-Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity. Analytical Chemistry, 2022, 94: 17263–17271.

12. Long Yu, Zhanheng Gao, Qi Xu, Xiangyu Pan, Yuxiu Xiao*. A Selective Dual-Response Biosensor for Tyrosinase Monophenolase Activity Based on Lanthanide Metal-Organic Frameworks Assisted Boric Acid-Levodopa Polymer Dots. Biosensors and Bioelectronics, 2022, 210: 114320.

13 Long Yu, Lixiang Feng, Li Xiong, Shuo Li, Shuo Wang, Zhongyu Wei, Yuxiu Xiao*. Portable Visual Assay of Bacillus Anthracis Biomarker Based on Ligand-Functionalized Dual-Emission Lanthanide Metal-Organic Frameworks and Smartphone-Integrated Mini-Device. Journal of Hazardous Materials, 2022, 434: 128914.

14 Anqi Huang, Wenwen Deng, Xiao Li, Qutong Zheng, Xuanxuan Wang, Yuxiu Xiao*. Long-chain Alkanolealkyl Carboxylic Acid-based Low-viscosity Hydrophobic Deep Eutectic Solvents for One-pot Extraction of Anthraquinones from Rhei Radix et Rhizoma. Journal of Pharmaceutical Analysis, 2022, 12: 87–95.

15. Long Yu, Qutong Zheng, Heng Wang, Chenxi Liu, Xiaoqing Huang, and Yuxiu Xiao*. Double-color Lanthanide Metal-organic Framework Based Logic Device and Visual Ratiometric Fluorescence Water Microsensor for Solid Pharmaceuticals. Analytical Chemistry, 2020, 92: 1402–1408.