Position: Associate Professor
School/Academic Group:School of Pharmaceutical Sciences
Email：mjgu@whu.edu.cn
Education:
2002–2006: Wuhan University, Bachelor
2006–2011: Wuhan University, Ph.D.
2010–2011: Visiting Doctoral Student, Department of Pathology, The Ohio State University, USA
Working Experience:
2011–2013 Wuhan University, Postdoc
2014–2015 Dana-Farber Cancer Institute, Harvard Medical School, USA, Postdoc
2014–2021 Wuhan University, Lecturer
Since 2022 Wuhan University, Associate Professor
Current Teaching Interests/Responsibilities:
Experiment of Biopharmaceutics
Research Interests:
Biomedical Applications of Novel Molecular Probes; Bacteriophage Infection Mechanisms and Applications
Publications:
1. Meijia Gu, Susu Jiang, Xiaoyu Xu, Ming-Yu Wu, Chao Chen, Yuncong Yuan, Qingrong Chen, Yidan Sun, Luojia Chen, Chao Shen, Peng Guo, Shujie Liu, Engui Zhao*, Shi Chen*, Sijie Chen*. Simultaneous Photodynamic Eradication of Tooth Biofilm and Tooth Whitening with an Aggregation-Induced Emission Luminogen, Advanced Science, 2022 May 7:e2106071. DOI: 10.1002/advs.202106071.
2. Libei Huang#, Meijia Gu#, Zhaoyu Wang, Tsz Wing Tang, Zonglong Zhu, Yuncong Yuan, Dong Wang, Chao Shen*, Ben Zhong Tang*, Ruquan Ye*. Highly Efficient and Rapid Inactivation of Coronavirus on Non-Metal Hydrophobic Laser-Induced Graphene in Mild Conditions, Advanced Functional Materials, 2021 Jun 9;31(24):2101195. DOI: 10.1002/adfm.202101195.
3. Meijia Gu*#, Libei Huang#, Zhaoyu Wang, Weihua Guo, Le Cheng, Yuncong Yuan, Zhou Zhou, Liu Hu, Sijie Chen, Chao Shen*, Ben Zhong Tang*, Ruquan Ye*. Molecular Engineering of Laser-Induced Graphene for Potential-Driven Broad-Spectrum Antimicrobial and Antiviral Applications, Small, 2021 Dec;17(51):e2102841. DOI: 10.1002/smll.202102841.
4. Ming-Yu Wu#, Meijia Gu#, Jong-Kai Leung, Xinmei Li, Yuncong Yuan, Chao Shen, Lianrong Wang*, Engui Zhao*, Sijie Chen*. A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses, Small, 2021 July;17(30):e2101770. DOI: 10.1002/smll.202101770.
5. Yishen Liu#, Qianqian Li#, Meijia Gu#, Disheng Lu#, Xiaoxing Xiong#, Zhiyun Zhang Yanna Pan, Yuqin Liao, Qihang Ding, Wanxia Gong, Dean Shuailin Chen, Mengting Guan, Junzhu Wu, Zhiquan Tian, Hai Deng, Lijuan Gu, Xuechuan Hong*, Yuling Xiao*. A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy, Journal of Medicinal Chemistry, 2022 Feb 10;65(3):2225-2237. DOI: 10.1021/acs.jmedchem.1c01736.
6. Meijia Gu, Hua Li, Chao Shen, Lin Wu, Wanhong Liu, Lixia Miao, Congyi Zheng*, Cloning and characterization of a new BRCA1 variant: A role for BRCT domains in apoptosis, Cancer Letters, 2010 Sep 28;295(2):205-13. DOI: 10.1016/j.canlet.2010.03.002.
7. Meijia Gu#, Ming-Yu Wu#, Yuncong Yuan, Po-Yu Ho, Zhou Zhou, Engui Zhao*, Chao Shen* and Sijie Chen*. Isoquinolinium-based photosensitizers with aggregation-induced emission characteristics for highly efficient photodynamic combat of viruses, Materials Chemistry Frontiers, 2022 Aug. DOI: 10.1039/d2qm00630h.
8. Meijia Gu, Meimei Yang, Jing He, Sixuan Xia, Zhe Zhang, Yudong Wang, Congyi Zheng, Chao Shen*. A silver lining in cell line authentication: Short tandem repeat analysis of 1373 cases in China from 2010 to 2019, International Journal of Cancer, 2022 Feb 1;150(3):502-508. DOI: 10.1002/ijc.33789.
9. Meijia Gu, Zixuan Zeng, Mai Xing, Yige Xiong, Zixin Deng, Shi Chen, Lianrong Wang*. The Biological Applications of Two Aggregation-Induced Emission Luminogens, Biotechnology Journal, 2019 Dec;14(12):e1900212. DOI:10.1002/biot.201900212.
10. Meijia Gu, Zixuan Zeng, Ming-Yu Wu, Jong-Kai Leung, Engui Zhao*, Shidong Wang, Sijie Chen*, Imaging Macrophage Phagocytosis Using AIE Luminogen-Labeled E.coli, Chemistry—An Asian Journal, 2019 Mar 15;14(6):775-780. doi: 10.1002/asia.201801859.
11. Meijia Gu, Ti He, Yuncong Yuan, Suling Duan, Xin Li*, and Chao Shen*, Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical Cancer, Frontiers in Oncology, 2021 Nov 26;11:753386. DOI: 10.3389/fonc.2021.753386.
12. Meijia Gu*#, Huaqin Pan#, Yuncong Yuan, Xuemin Zhou, Luojia Chen, Xingran Wang, Fang Fang, Liu Hu, Yaxuan Xie, Chao Shen*, Sera Metabolomics Characterization of Patients at Different Stages in Wuhan Identifies Critical Biomarkers of COVID-19, Frontiers in Cellular and Infection Microbiology, 2022 May 2;12:882661. DOI: 10.3389/fcimb.2022.882661. eCollection 2022.
13. Meijia Gu, Jingxuan Liu, Meimei Yang, Mingmin Zhang, Jian Yang, Suling Duan, Xuxu Ding, Jie Liu, Chuguang Chen, Yundian Zeng, Chao Shen*, Advantages of a 21-loci short tandem repeat method for detection of cross-contamination in human cell lines, Gene, 2020 Dec 30;763:145048. DOI: 10.1016/j.gene.2020.145048.
14. Meijia Gu, Chao Shen*, Novel cancer cell lines derived from primary breast tumors in Chinese patients, American Journal of Translational Research, 2018 Dec 15;10(12):3956-3968.
15. Zixuan Zeng, Xiaojiao Ren, Tailang Yin, Xiang Gao, Mengting Tsai, Yi Zhang, Meijia Gu*, Multiplexed detection and the establishment of a novel high-throughput method for human germ cell quality screening based on aggregation-induced emission, American Journal of Translational Research, 2019 Nov 15;11(11):6907-6923.
