Position: Associate Researcher

School/Academic Group: School of Pharmaceutical Sciences

Email： wangzhiming@whu.edu.cn

Education:

2009-2015: Institute of Biophysics, Chinese Academy of Sciences, Ph.D.

2007-2009: Wuhan University, Bachelor

2005-2009: Wuhan University of Technology, Bachelor

Working Experience:

2022-Present: Wuhan University, Associate Researcher

2020-2021: Nanjing GeneMax Biotechnology Co., Ltd. Senior Scientist

2016-2020: University of Colorado, USA, Postdoc

2015-2016: Institute of Biophysics, Chinese Academy of Sciences, Research Assistant

Research Interests:

Molecular immunology, structural pharmacology

Molecular mechanisms of metal transporters related to nutritional immunity

Molecular mechanisms of host cell defense against pathogens

Publications: (* Co-first author)

1. Zhiming Wang, Wenxin Hu, Hongjin Zheng. Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Science Advances, 6, eaay7997 (2020)

2. Zhiming Wang*, Jeremy Rahkola* et al. Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. Nature Communications 11 (1), 1-8 (2020)

3. Zhiming Wang, Zhu Qiao, Sheng Ye and Rongguang Zhang. Structure of a double- domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains. Acta Cryst.(2015). D71, 779-789

4. Xue Dong*, Zhiming Wang*, Sheng Ye, Rongguang Zhang. The crystal structure of ORP3 reveals the conservative PI4P binding pattern. Biochemical and Biophysical Research Communications 529 (4), 1005-1010 (2020) * Co-first authors

5. Wenxin Hu, Zhiming Wang, Hongjin Zheng. Mitochondrial accumulation of amyloid β (Aβ) peptides requires TOMM22 as a main Aβ receptor in yeast. Journal of Biological Chemistry, 2018, 12681-1289

6. Wenxin Hu, Zhiming Wang, Hongjin Zheng. Mechanosensitive channel YnaI has lipid-bound extended sensor paddles. Communications Biology 4, 602 (2021)